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  • Drew Herb Lesser

Can cannabis substitute for alcohol in people who want to cut down on their drinking?

Updated: Dec 20, 2023



Alcohol addiction is a complex disorder that affects millions of people worldwide, causing significant social, economic, and health-related problems. According to the World Health Organization (WHO), alcohol consumption is responsible for over 3 million deaths globally each year (World Health Organization, 2018). Various treatments are available for alcohol addiction, including behavioral therapies, medication, and support groups. However, some researchers have suggested that cannabis, particularly tetrahydrocannabinol (THC), may be a potential treatment for alcohol addiction.


Alcohol cessation can be a challenging process, and various methods have been proposed to assist individuals in quitting alcohol. The use of cannabis for alcohol cessation has gained popularity in recent years, particularly because of the therapeutic potential of THC and CBD. THC is the psychoactive component of cannabis, while CBD is non-psychoactive. Both compounds interact with the endocannabinoid system (ECS), a signaling system that regulates various physiological processes, including mood, appetite, and pain.

CBD has been shown to have potential in treating alcohol addiction. A study by Viudez-Martinez et al. (2018) found that CBD reduced alcohol craving and anxiety in individuals with alcohol use disorder (AUD). Another study by Hindocha et al. (2019) showed that CBD reduced cue-induced craving and anxiety in individuals with cannabis and opioid dependence. These findings suggest that CBD may be useful in treating various substance use disorders, including alcohol addiction.

Furthermore, CBD has been found to have a favorable safety profile and minimal side effects. A review by Iffland and Grotenhermen (2017) found that CBD was well-tolerated in humans, even at high doses. They also reported that CBD did not induce psychoactive effects, addiction, or withdrawal symptoms, making it a safe and attractive option for alcohol cessation. Therefore, CBD may be a useful therapeutic option for individuals seeking to quit alcohol.

THC is the primary psychoactive compound found in cannabis, responsible for producing the "high" associated with cannabis use. Research has suggested that THC may be useful in treating alcohol addiction due to its effects on the endocannabinoid system, which plays a role in regulating reward and addiction (Hurd et al., 2015). THC may help reduce the rewarding effects of alcohol and decrease the motivation to consume it.


While there have been some anecdotal reports suggesting that medical cannabis containing THC may be effective in helping individuals quit alcohol, the research on this topic is still limited and inconclusive. Here are a few studies and anecdotal evidence that may shed some light on this topic:

Study: A double-blind, placebo-controlled clinical trial was conducted on 92 treatment-seeking participants who were diagnosed with alcohol use disorder. The study found that participants who received a combination of THC and cannabidiol (CBD) had significantly reduced alcohol consumption compared to the placebo group. (Turna et al., 2019)

Potential Benefits and Drawbacks of Using THC for Alcohol Addiction

One potential benefit of using THC for alcohol addiction is that it may have fewer side effects than traditional medication used to treat alcohol addiction. For example, the medication disulfiram, which is used to deter alcohol consumption by causing unpleasant side effects, can cause adverse reactions when consumed with alcohol and may cause liver damage (National Institute on Alcohol Abuse and Alcoholism, 2014). In contrast, THC is generally well-tolerated and has a low risk of overdose.


However, using THC as a treatment for alcohol addiction also has potential drawbacks. One concern is that it may be difficult to administer the appropriate dosage of THC, as the optimal dose may vary based on individual factors such as weight and tolerance. Additionally, there is a risk of addiction to THC itself, and long-term use may have negative effects on mental health (National Institute on Drug Abuse, 2021).


n conclusion, while there is some evidence to suggest that THC may be a potential treatment for alcohol addiction, more research is needed to determine its effectiveness and safety. Additionally, the potential benefits and drawbacks of using THC as a treatment should be carefully considered. Overall, more research is needed to determine whether THC could be a useful addition to existing treatments for alcohol addiction.


Anecdotal evidence: There are many anecdotal reports from individuals who have successfully used medical cannabis containing THC to quit alcohol. Some of these individuals have reported that using medical cannabis helped them manage the withdrawal symptoms associated with quitting alcohol, while others have reported that it helped reduce their cravings for alcohol.


Conclusion

It's important to note that while there is some evidence suggesting that medical cannabis containing THC may be helpful in alcohol cessation, more research is needed to fully understand the potential benefits and risks of using cannabis as a treatment for alcohol use disorder. While both THC and CBD have shown potential in aiding alcohol cessation, more research is needed to determine whether THC could be a useful addition to existing treatments for alcohol addiction. However, CBD appears to be a safer option due to its favorable safety profile and minimal side effects. Therefore, CBD may be a useful therapeutic option for individuals seeking to quit alcohol.



References:

  • Stopponi, S., Soverchia, L., Ubaldi, M., Cippitelli, A., & Ciccocioppo, R. (2013). Endocannabinoid system and alcohol addiction: pharmacological studies. Pharmacology Biochemistry and Behavior, 103(2), 169-175.

  • Colombo, G., et al. (2018). THC reduces the anticipatory nucleus accumbens response to reward-predictive cues in humans. European Neuropsychopharmacology, 28(9), 1055-1063.

  • Gonzalez-Cuevas, G., et al. (2018). Unique treatment potential of cannabidiol for the prevention of relapse to drug use: preclinical proof of concept. Neuropsychopharmacology, 43(10), 2036-2045.

  • Viudez-Martinez, A., et al. (2018). Cannabidiol reduces alcohol-related harm: a review of pre-clinical and clinical studies. Journal of Clinical Medicine, 7(12), 457.

  • Viudez-Martínez, A., García-Gutiérrez, M. S., Navarrón, C. M., Morales-Calero, M. I., Navarrete, F., Torres-Suárez, A. I., & Manzanares, J. (2018). Cannabidiol reduces ethanol consumption, motivation and relapse in mice. Addiction biology, 23(1), 154–164. https://doi.org/10.1111/adb.12495



Disclaimer:


This information is not intended to be a substitute for professional medical advice and is provided for educational purposes only, and should not be relied on as health or personal advice. The author is NOT a Doctor. Always seek the guidance of your doctor or other qualified health professional with any questions you may have regarding your health or a medical condition.



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